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And human studies are scarce

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doi: 10.1038/s41586-019-1707-0

By targeting IL-1, interleukin-18 (IL-18), and type I interferon pathways, probiotics can fine-tune inflammasome activity, thereby suppressing aberrant inflammatory responses while simultaneously strengthening host antiviral defenses (236)

American gastroenterological Association-American college of gastroenterology clinical practice guideline: Pharmacological management of chronic idiopathic constipation

Its important for users to discuss potential side effects with their healthcare provider and report any severe reactions