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Interaction between glutathione and apoptosis A decrease in cellular GSH concentration has long been reported to be an early event in the apoptotic cascade induced by death receptor activation [5], mitochondrial apoptotic signaling [110], and oxidative stress [62,111]

PMID 15455129)

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10.1007/s12264-018-0269-8 78 WuH.WeiM.LiN.LuQ.ShresthaS

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Environ Pollut 308:119606 Cobbett CS, May MJ, Howden R, Rolls B (1998) The glutathione deficient, cadmium-sensitive mutant, cad2-1, of Arabidopsis thaliana is deficient in -glutamylcysteine synthetase