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Description

as fat mass decreases rapidly, these signals change

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Elevated expression of macrophage MERTK exhibits profibrotic effects and results in defective regulation of efferocytosis function in pulmonary fibrosis

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Supported by trials like EMPA-REG, LEADER, and CANVAS, though large dedicated combination trials are still ongoing.

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Kullmann S, Heni M, Hallschmid M, Fritsche A, Preissl H, Hring H-U

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Sp1/Sp3 transcription factors regulate hallmarks of megakaryocyte maturation and platelet formation and function

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