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Endogenous glucagon-like Peptide-1 suppresses high-fat food intake by reducing synaptic drive onto mesolimbic dopamine neurons

After consulting with a weight loss physician, I hesitantly started taking a glucagon-like peptide-1 (GLP-1) receptor agonist (Zepbound, in my case) approximately two years ago, and, in short, its been life-changing for me in the best way

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This means that the age-related changes you start to see and feel (especially after the age of 40) are primarily driven by declining cellular resilience and reduced repair capacity