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Disorders such as bacterial cystitis, urinary calculi, vaginitis, and less common problems like carcinoma in situ of the bladder and chronic bacterial prostatitis have significant symptom overlap and must be systematically excluded or identified and treated appropriately

Evid-Based Pract

This combined exposure has produced some encouraging results with amelioration of some neurological abnormalities and marked attenuation or disappearance of the vascular lesions and diarrhea [150] , suggesting disease modification from the invariably fatal clinical course of EE [151]

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