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Margin Expansion Is Structural, Not Cyclical

Persistent nausea can also signal dehydration, medication interactions, or underlying conditions unrelated to semaglutide

Insulin, which remains top of mind for possible GLP-1 impact, saw only a slight reduction in use post GLP-1 adoption

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Although more functional studies are needed to map the Angptl4 encounter site to LPL (20), recent Hydrogen Deuterium Exchange (HDX) Mass Spectrometry (HDX-MS) studies suggest that Angptl4 interacts with the lid (aa 89102) and -helix domain (aa 226238) of LPL (21)

Sean Hashmi, MD, is the regional medical director of Lifestyle & Obesity Medicine for the Southern California Permanente Medical Group, and national chair of the interregional clinical practice group for Lifestyle & Obesity Medicine, The Permanente Federation.