A randomized controlled trial published in the Journal of Veterinary Internal Medicine found that supplementing systemically ill dogs with N-acetylcysteine (NAC), a direct precursor to glutathione, maintained their glutathione levels through acute stress
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Due to the effect of the virus on T lymphocytes and consequent disruption of the immune system, infected patients may become susceptible to bacterial infections
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Studies have shown that reductions in CSF ferritin following antioxidant therapy (e.g., N-acetylcysteine) or iron chelation (e.g., deferoxamine) correlate positively with improvements in cognitive performance, supporting their use as dynamic indicators of clinical efficacy (Du et al., 2024)
