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In vitro skin irritation test provides an alternative to animal testing and allows the screening of compounds before they undergo clinical testing

For patients requiring an SSRI, pharmacists should consider using paroxetine, citalopram, or escitalopram and minimizing the use of fluoxetine and sertraline when appropriate

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a , Mitochondrial abundance of GSH in HEK-293T SLC25A39 knockout cells expressing a vector control or SLC25A39 cDNA treated with GSH (5 mM) or GSHee (5 mM) for 24 h