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The top concern is the lack of research on the effectiveness or safety of microdosing the drugs (or using GLP-1s, period) in people with normal weight and blood sugar
Given that nausea, vomiting, diarrhea, and constipation are common adverse effects of GLP-1 medicationsparticularly during dose titrationselecting a magnesium supplement that does not exacerbate these symptoms is clinically prudent
J Clin Pharmacol (2008) 48(12):138999
That's why both Hatipoglu and Siegel recommend discussing any dose changes with a healthcare provider rather than experimenting on your own
CrossRef The Bubble-Destruction Curve Obtained Using Contrast-Enhanced Ultrasound is Useful for Assessing Liver Fibrosis and Identifying At-risk MASH in Patients With MASLD Noritaka Wakui, Yu Ogino, Naohisa Kamiyama, Takuma Oguri, Tomoya Uchimura, Takahide Kudo, Kenichi Maruyama, Hideki Nagumo, Naoyuki Yoshimine, Kunihide Mouri, Kojiro Kobayashi, Takanori Mukozu, Teppei Matsui, Hidenari Nagai, Yoshinori Igarashi, Takahisa Ma Ultrasound in Medicine & Biology .2026
