Restrictive eating disorders A joint advisory from obesity and nutrition societies notes that restrictive eating disorders are a general contraindication to GLP-1 use
This is the receptor neither semaglutide nor tirzepatide touches
36 Moreover, GLP-1 RAs improve lipid profiles by decreasing serum cholesterol and triglyceride levels and increasing high-density lipoprotein (HDL) levels contributing to cardiovascular protection
Just like we have learnt to advise hypertensive or hyperlipidemic patients on a healthy lifestyle but start therapy immediately, we need to recognize that many obese patients have wrestled with this for a lifetime, have tried multiple lifestyle interventions already
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Are there other factors sitting on the brake of my desire and motivation undiagnosed or undertreated ADHD, anxiety, complex feelings in a relationship, burnout, low testosterone or estrogen, thyroid issues