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The data supports its role in skin firmness and hair density appearance when used at clinical concentrations

10.2337/db16-0058 65 HayashiN.NakamoriS.HiraokaN.TsujieM.XundiX.TakanoT.et al (2004)

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All bond lengths were constraint using the linear constraint solver (LINCS) algorithm 39

"For example, if a dog has a LVIDDN that consistently oscillates around 1.3 (within 0.1 units), an increase to 1.6 could indicate left ventricular enlargement for that dog, despite being within the population-based reference interval." (27) Noriko Isayama, Yusuke Uchimura, Kenta Sasaki, Erika Maeda, Toshihisa Takahashi, Megumi Watanabe