In line with these studies, we observed that the combination of sertraline plus chloroquine diminished the levels of NADH, and both sertraline and chloroquine treatments induced depletion of aspartate and malate, with an even more pronounced effect in the combination therapy
How This Study Fits in the Copper Peptide Evidence Base This study adds a unique piece to the copper peptide puzzle: it demonstrates the concept of using energy-based devices (radiofrequency) to deliver copper peptide serums, rather than relying on simple topical application
This requires NADPH, making mitochondrial and cellular energy metabolism relevant to antioxidant resilience
These restrictions, especially for that of BCS Class III drugs, merit regulatory relief
A compound engineered to do the opposite, to push that pathway harder in order to grow synapses, is making a bet that you can rev a known cancer-promoting system in the brain without consequences elsewhere in the body, the same uncomfortable tradeoff we examined in our piece on whether peptides cause cancer
One familiar example is copper peptides, which have been used in dermatology for years to support skin health and repair