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In high-grade dysplasia (HGD), there are marked cytologic changes (Figure 3): enlarged, hyperchromatic, and pleomorphic nuclei with at least focal loss of polarity, increased and atypical mitosis, and crowding of glands with almost complete loss of lamina propria

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Consequently, targeting gut microbiota has emerged as a promising therapeutic strategy for treating kidney diseases

However, it is essential to consult with a healthcare provider to determine if this treatment is appropriate for your specific situation

Semaglutide mimics the effects of a hormone called GLP-1 (glucagon-like peptide-1), which stimulates insulin secretion, inhibits glucagon release, slows gastric emptying, and reduces appetite