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For example, lets say there are two GLP-1s, similar in safety and efficacy

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The consequences of the cardiovascular disease-related reductions in CBF include accelerated reduction in frontal, parietal, and temporal grey matter volumes (Moroni et al., 2018), cognitive deficits (Jiang et al., 2023), and increased risk of ADRD (Brain et al., 2023)

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Multisensory convergence at human temporo-parietal junction - epicortical recording of evoked responses