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Additional Phase 3 trials are still underway, including TRIUMPH-2 (evaluating retatrutide in adults with obesity and type 2 diabetes) and TRIUMPH-3 (evaluating cardiovascular outcomes), with results expected later in 2026

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2024;16(16) doi: 10.3390/nu16162809

The authors characterized in vitro receptor pharmacology across GIPR, GLP-1R, and GCGR, and reported results in diet-induced obese rodent models comparing the triple agonist with a selective GLP-1R agonist