Meanwhile, GST catalyzes the formation of platinum-GSH compound and accelerates drug inactivation via increasing drug solubility (Rabik and Dolan, 2007)
Primarily, GLP-1 RAs help regulate blood glucose levels by stimulating insulin secretion from pancreatic beta cells, whilst decreasing the production of glucagon, a hormone that increases blood glucose
Patients can usually be divided into two groups when starting GLP-1 RAs: those with depression and those without
Allantoin: Great for acne scars
-Surveillance data (e.g., Australias TGA) show dozens of reports of eye disorders in people using semaglutide (including optic ischaemic neuropathy, blindness/visual impairment) though these are spontaneous reports, so causality is uncertain
Abstract GLP-1 receptor agonists (e.g., semaglutide) and dual GLP-1/GIP receptor agonists (e.g., tirzepatide) are effective for reducing body weight and fat mass, though lean soft tissue loss comprised 26%40% of weight loss in recent trials