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This imbalance might cause LPS to be increasingly produced and enter the bloodstream, triggering widespread inflammation through IL-10, disruptions in the HPA axis, and a reduction in cortisol levels, another factor linked with ME/CFS [79, 80]

Medically Reviewed | Updated: February 2026 Category: GLP-1 & Weight Loss | Reading Time: 8 min If youre preparing to start a GLP-1 receptor agonist whether thats semaglutide (Ozempic, Wegovy), tirzepatide (Mounjaro, Zepbound), or another agent in this class baseline lab testing is one of the most important steps you can take before your first dose

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