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It has a critical role in protecting cells from oxidative stress and maintaining the immune system

Early evidence shows that people taking these drugs are eating less beef, choosing more vegetables, and turning away from processed snacks

Hence, low levels of serotonin, a substance essential in elevating mood, may be produced in people with vitamin B12 insufficiency

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On 29 January 2026, the MHRA updated product information for GLP-1s and issued a drug safety alert to highlight that acute pancreatitis is a known but infrequent side effect that can be fatal, stressing that patients and clinicians should be alert to initial symptoms, such as severe, persistent stomach pain that may radiate to the back and may be accompanied by nausea and vomiting 26

How Rybelsus and Other Semaglutides Work Rybelsus is a glucagon-like peptide-1 receptor agonist (GLP-1, or sometimes GLP-1 RA)