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Effects of combination therapy on intermediate endpoints and side effects according to meta-analyses of randomized trials We analysed data from 6 meta-analyses (Table 1), which assessed the effect of the combination therapy on HbA1c and body weight

Gonzalez-Casimiro CM, Merino B, Casanueva-Alvarez E, Postigo-Casado T, Camara-Torres P, Fernandez-Diaz CM, et al

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While tirzepatide does not directly target these pathways, the metabolic improvements and weight reduction it facilitates may indirectly support healthier reproductive hormone profiles

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