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In other study groups, only 25-50% of participants lost more than 10% of their body weight

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Effects of adding linagliptin to basal insulin regimen for inadequately controlled type 2 diabetes: a 52-week randomized, double-blind study

According to the Semaglutide Treatment Effect in People with Obesity (STEP) 1 study, once-weekly semaglutide combined with lifestyle management led to significant weight loss in obese people

For weight management in people without diabetes , NICE recommends considering semaglutide 2.4 mg (Wegovy) for adults with a BMI 35 kg/m (or lower thresholds for certain ethnic groups) and at least one weight-related comorbidity

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