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These effects tend to be dose-dependent, class-dependent, and are more frequent during the initial stages of treatment [114, 118]

DES, an estrogen medication, was used from 1940 to 1971 for pregnant women

They sporadically checked, when possible, at the day's beginning or end (Table 8)

To prevent oxidative stress and the inflammatory response in acute and chronic progressive diseases, approaches to enhance the expression of Nrf2 and thereby inhibit ferroptosis should undoubtedly play a central role in treating ALI, COPD, and idiopathic PF in the future