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In the blood, once secreted from the pineal gland, melatonin is usually bound to albumin, metabolized to 6-hydroxymelatonin by cytochrome P-450 isoforms and conjugated, in the liver, to produce the principal urinary metabolite, 6-sulfatoxy-melatonin, which is finally eliminated through the kidney 14

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But a handful of these products do provide real, scientifically proven benefits for athletes, such as faster post-exercise recovery, enhanced workout performance and reduced risk of injury