Conversely, Cur markedly decreased the TUNEL-positive cells similar to that observed in a glycol-induced nephrotoxic rat model by activation of PI3K/Akt pathway resulting in attenuation in release of pro-apoptotic caspases, inhibition of tumor necrosis factor-gamma signaling pathway and reduction of Bax/Bcl-2 ratio (Awad & El-Sharif, 2011
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To deepen assess the impact of gpoA deletion on bacterial pathogenesis, we examined the intracellular survival of the gpoA mutant in three different host cell types: human pneumocytes (A549
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