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Metabolic health improvements such as balanced blood sugar, cholesterol, and blood pressure

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When researchers blocked that pathway, berberine's GLP-1-stimulating effect disappeared completely

Since diabetes is frequently complicated by renal disease, consider a lower starting dosage and gradual increase in dosage for patients with renal impairment [see Dosage and Administration (2.7) and Use in Specific Populations (8.10)]

Patients must be adequately hydrated while on semaglutide and are advised to seek medical attention immediately in cases of abdominal pain radiating to the back

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