The experiment described was conducted on the synapse between the perforant path and dentate gyrus in the hippocampi of anaesthetised rabbits
NAC (150 mg/kg/day) was given to male rats that had been administered valproate during pregnancy to simulate ASD
In some embodiments, otic formulations or compositions described herein increase the bioavailability and/or steady state levels of a drug in auris structures (e.g., in inner ear and/or the endolymph and/or the perilymph)
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The science behind this program addresses the specific physiological changes caused by GLP-1 receptor agonists, such as slowed digestion and altered insulin release
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