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While the exact location of the neurological injury has yet to be identified since MRI (0.5 T) assessments conducted in 1993 on 2 konzo-affected individuals reported no pathological findings, the phenotypic presentation of various severities (Stages 13) of hyperreflexia and non-spastic paraparesis suggests damage of motor neurons and corresponding brain regions

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Koren HS, Hatch GE, & Graham DE (1990) Nasal lavage as a tool in assessing acute inflammation in response to inhaled pollutants