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These immune responses Led to An approximate 62% reduction in tumor volume following light irradiation, with no notable toxicity or changes in body weight, confirming both strong therapeutic efficacy and favorable biosafety [46]

4.3 Sterol mutations and amphotericin B resistance in Leishmania Resistance to amphotericin B (AmB) in Leishmania primarily involves mutations in the sterol biosynthesis pathway, resulting in altered membrane sterol composition

This was not just observed in animal models

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Br J Pharm Res

Thus, kidney-derived GPX3 can be transported to other tissues and bound to the basement membrane