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For gene ontology (GO) analysis, the Seurats FindMarkers output for the specified groups was used to plot gene ontology terms with the barcodeplot functions from limma 131

Biologic lipid-modulating therapies are evolving beyond lowering LDL-C to encompass interventions targeting triglyceride-rich lipoproteins (TRLs), Lp(a), and HDL metabolism

The endothelial cell dysfunction induced by oxidized LDL is one of the first steps in the development of arteriosclerosis, so the adaptive vascular responses and /or oxidative stress protectors are important in the prevention of arteriogenesis (55)

By mimicking natural hormones, it signals your brain to feel full, helping you eat less and stay on track with your weight loss plan

Collectively, the evidence is cautiously reassuring for major anomalies but insufficient to exclude uncommon risks or provide agent-specific safety estimates