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There are several common pathological processes in AD and type 2 diabetes mellitus (T2DM), including impaired glucose metabolism, insulin resistance, mitochondrial dysfunction, increased oxidative stress, and increased neuroinflammation [6]
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Notably, knockdown of Gdh1 in different mouse cell lines (HepaMP9-1, 3T3 and KL-155) did not alter AMPK expression (Extended Data Fig
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The injection process itself is straightforward
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