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Weight reduction and reduced adiposity probably contributed significantly, but additional mechanisms may also be involved, such as improved insulin sensitivity, reduced inflammation, reduced aromatization for the adipose tissue, and potentially a restoration or improvement of the hypothalamic-pituitary-gonadal axis," he noted

doi: 10.1038/s41416-022-01747-0 120 TianSPengPLiJDengHZhanNZengZet al

In WAT, dopamine enhanced insulin-mediated glucose uptake also via D2R [11]