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Assessment of lipid peroxidation via the C11-BODIPY lipid peroxidation sensor revealed an increase in the C11-BODIPY signal following SHP2/MEK inhibition compared with that in the DMSO control group, which reached statistical significance in 2/7 of the cell lines (Fig

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Efficacy of Currently Approved Therapies for Obesity Orlistat Orlistat is a selective inhibitor of pancreatic lipase, which thereby moderates the intestinal digestion and absorption of fat, approved for use by both the FDA and EMA

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