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Common GI Side Effects Nausea, vomiting, diarrhea, constipation, abdominal pain, distension, dyspepsia, flatulence, and belching hit up to 50% of users during dose escalation

After first puncture, the 28-day multi-dose window starts, and refrigeration at 2-8C is consistently cited as the documented best practice in community and pharmaceutical references

73 In patients with reflux-predominant symptoms unresponsive to lifestyle modification, proton pump inhibitors or histamine-2 receptor antagonists may be used

Muniyappa, who studies endocrine disorders and runs the diabetes services at the National Institute of Diabetes and Digestive and Kidney Diseases, recommended against bariatric surgery because of the patients age and comorbidities

It's also approved for reducing cardiovascular event risk in adults with cardiovascular disease who are overweight or obese

Response can vary