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Supportive secondary endpoints (trial product estimand) The mean changes in FPG and 7-point SMPG from baseline to 26 weeks were significantly greater with oral semaglutide (all doses) than with sitagliptin 100 mg (Table 2

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noteworthy low testosterone levels might further influence weight gain besides PRL excess in these patients, as body weight, BMI, and waist circumference have been found to be significantly higher as compared to non-hypogonadal patients after treatment with CAB and testosterone replacement (52)

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