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Neither action affects currently approved / existing waivers but both may limit new HRSN / SDOH state waiver requests or waiver extension requests

Dosing is extrapolated from preclinical models [1] [6]

Also, when cells acquire their cysteine via GSH breakdown, they are no longer sensitive to inhibitors of cystine uptake

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Review Article - (2016) Volume 8, Issue 2 John W Wright 1,2* and Joseph W Harding 1,2 1 Departments of Psychology and Integrative Physiology and Neuroscience, and Program in Biotechnology, Washington State University, Pullman, WA, USA 2 M3 Biotechnology, Inc., Seattle, WA, USA Received May 02, 2016