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paracasei LMG-S-26420 was grown in a Sartorius fermenter (Biostat A Plus model) for 24 h at 37 C, at pH 5.5, and controlled by 5M NaOH
In the REDEFINE 1 trial, published in the New England Journal of Medicine, participants receiving the combination achieved 20.4% mean body weight reduction at 68 weeks
Sip water throughout the day, and consider adding electrolytes especially if youve increased your water intake on a GLP-1
In SURMOUNT-1 , a 72-week Phase 3 double-blind trial in 2,539 adults with obesity (or overweight with a complication) but without diabetes, once-weekly tirzepatide produced mean weight changes of 15.0% (5 mg), 19.5% (10 mg), and 20.9% (15 mg) versus 3.1% with placebo, with 5057% of participants on the higher doses losing at least 20% of body weight
Most people think of GLP-1 as a gut hormone involved in blood sugar regulation and satiety