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In addition, mice with T2DM treated with dapagliflozin for eight weeks demonstrated significantly less arterial stiffness, improvements in endothelial and vascular smooth muscle dysfunctions, and reductions in circulating markers of inflammation compared with non-treated diabetic mice (55)

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References Costa, T

Now, researchers at UC San Diego are exploring whether semaglutide, the active ingredient in those medications, could also help slow biological aging

This SGLT1-dependent mechanism is the basis for the early elevation of plasma GLP-1 and GIP levels after carbohydrate intake (Zhu et al., 2022)

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