If you have a lot of gas, acid reflux, belching, loose motion and/or constipation, brain fog, migraines and/or joint pains, you probably have a gut issue like SIBO, leaky gut or irritable bowel syndrome (IBS)

Contact your GP or prescribing clinician urgently if you experience: Severe or persistent abdominal pain , particularly if it radiates to the back or is accompanied by vomiting Signs of pancreatitis : intense upper abdominal pain, nausea, vomiting, and fever (this is a rare but serious adverse effect of GLP-1 receptor agonists) Persistent vomiting that prevents you from keeping down food or fluids, risking dehydration Blood in vomit or stools , which could indicate gastrointestinal bleeding Severe diarrhoea lasting more than 48 hours, particularly if accompanied by dehydration symptoms Symptoms of gallbladder disease : pain in the upper right abdomen, particularly after eating fatty foods, along with nausea or jaundice If pancreatitis is suspected, stop Saxenda immediately and seek urgent medical review
That is the proposed reason it does not raise IGF-1 levels or impair insulin sensitivity in animal work, in contrast to full-length growth hormone
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