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Some patients also notice improvements in hair thickness and nail strength

Symptoms of magnesium toxicity include nausea, hypotension, bradycardia, respiratory depression, and in severe cases, cardiac arrest

This may be the result of disturbed function of the ThDP-dependent 2-oxoglutarate dehydrogenase (Figure 1), as a universal effect of its inhibition is perturbation in relative amino acid abundance and a subsequent decrease in protein synthesis (196, 197)

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Always consult with your healthcare provider if you experience any unusual symptoms

Patients who prefer a symptom-free morning should consider evening dosing as an alternative