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Reductions exceeded 80% with 8 mg and 12 mg

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By 12 months, 60% of patients were able to maintain a treatment response

Read: Catalent x Novo: the GLP-1 wars heat up What are GLP-1 agonists

It also calls constipation one of the most common reasons patients discontinue GLP-1 therapy, which is why it frames the problem as something to plan for with a provider before starting rather than react to later