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The specific combination of cagrilintide with retatrutide has no published clinical trial data and does not exist as a registered investigational programme

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No major toxicological red flags have been identified in preclinical studies

But in the case of B12 deficiency, homocysteine may rise beyond normal levels, causing irritation to the cardiovascular system and increasing inflammation

The standard NHS pattern is a loading phase (injections on alternate days for up to two weeks), followed by maintenance