Potential Side Effects and Considerations While probiotics are generally safe, some individuals may experience mild digestive discomfort initially
Tarng DC, Liu TY, Huang TP
Beyond mechanics, adipose tissue (body fat) is metabolically active
The vial can be kept at room temperature for short periods, such as during travel or immediately before injection, but prolonged exposure to room temperature should be avoided
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Exposure to TMAO decreases pyruvate metabolism ( via impaired substrate flux through pyruvate dehydrogenase), impairs -oxidation, and affects energy metabolism in cardiac muscle fibers, leading to the development of HF (Makrecka-Kuka et al., 2017)