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10.1016/j.jdermsci.2014.01.011 40 YuN.HuT.YangH.ZhangL.SongQ.XiangF.et al (2020)

#7 Genetic Factors Genetic variations or mutations in genes associated with enzymes involved in glutathione synthesis can impact its production

Only the concentration and the peptide identity change

Acute or short term side effects may include: Stomach or abdominal pain Nausea or stomach upset Indigestion Constipation Headache Dizziness Drowsiness Fatigue Tinnitus Fluid retention Long term side effects may include: Chronic stomach pain, heartburn, or nausea Increased risk of gastrointestinal bleeding Small bowel inflammation (1) Increased risk of stomach ulcers Increased risk of heart disease and cardiovascular events including heart attack, stroke, and heart failure Increased risk of kidney disease or kidney failure Neither of these are complete lists, and some people may be at a higher risk of experiencing serious side effects

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Lifestyle choices, such as diet and sleep, also play a role in how a person feels while taking the medication