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Several mechanisms have been proposed to explain chronic hyperglycemia-induced nerve damage, such as intracellular accumulation of sorbitol, glycation reactions, and oxidative and nitrosative stress (reviewed in 69)

2007 Oct-Dec;113(4-5):234-58

The Universal Anti-Oxidant Alpha Lipoic Acid (ALA) is a natural antioxidant and anti-inflammatory compound which works to alleviate pain, protect the brain, decrease the risk of cardiovascular disease, help with weight loss, improve diabetes, fight cancer, and assist in the treatment of several other health conditions

limited human data reveal no teratogenicity at therapeutic doses, yet clinicians are advised to employ the lowest effective regimen

Glutathione is a naturally occurring antioxidant found in every cell of the body