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DSIPs mechanism of action in the CNS appears to warrant intranasal application as a non-invasive means to directly cross the BBB

The animal data is promising, but promising animal data describes countless compounds that failed in humans

In addition to his P7CB 4-iron, Morikawa added a full set of P7CB irons 5-PW for the Scottish Open where he finished T4 and played them at the Open Championship as well

The gap between effective and ineffective use comes down to understanding that the dihexa half life dictates dosing frequency, but therapeutic outcomes are determined by what happens at the synaptic level during those brief exposure windows

doi: 10.1136/bmj.325.7372.1073