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I would not recommend vitamin B12 for patients based on this evidence, but will follow developments about this potential adjunctive therapy. Rheumatologist Dr Samuel Whittle, of The Queen Elizabeth Hospital in South Australia, told Rheumatology Republic there were several problems with the study

For example, glucose is the main substrate that photoreceptors utilize to create ATP in vivo 12 , but they can oxidize lipids, lactate, and use amino acids, fatty acids (such as palmitate) and other intermediate substrates to produce ATP, especially under glucose-deprived conditions 10,11,12

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