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Two common adjustments include stepping down, where the dose is gradually lowered while monitoring for cravings, or stretching out, which involves extending the time between doses (e.g., moving from weekly to every 1014 days)

Replenish nutrients lost during GLP-1 weight loss

PMC 3262859

Currently, there are ten classes of orally available pharmacological agents to treat T2DM: 1) sulfonylureas, 2) meglitinides, 3) metformin (a biguanide), 4) thiazolidinediones (TZDs), 5) alpha glucosidase inhibitors, 6) dipeptidyl peptidase IV (DPP-4) inhibitors, 7) bile acid sequestrants, 8) dopamine agonists, 9) sodium-glucose transport protein 2 (SGLT2) inhibitors and 10) oral glucagon like peptide 1 (GLP-1) receptor agonists

The supporting foundation was not involved in study design, the collection, analysis, or interpretation of data, writing of the report

Diabetologia 66 , 20072016 (2023)