Instead, patients might have been experiencing suicidal ideation prior to GLP-1 use, or experienced an unrelated external stressor while on the medication
The study demonstrated a clear benefit for semaglutide, with a 24% lower risk to reach the primary outcome in the semaglutide group versus the placebo group
For a 200-pound patient, this means 30-40 pounds lost
For example, some wellness or aesthetic clinics will prescribe GLP-1s for weight-loss without documenting an actual condition
This last year, I have gone from a size 18 to a size 4
Sound mechanistic evidence supports the need for further research on the GLP1-RAs/SGLT2is combinations ability to modify specific risk outcomes, such as cardiovascular risk and the progression of diabetic kidney disease