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In summary, our study suggests that PPARa promotes recovery by inhibiting neuronal ferroptosis caused by disrupted lipid metabolism after TSCI through the FSP1-CoQ10-NAD(P)H pathway

To evaluate whether combining distinct immune signals could enhance tumor cell killing, we tested whether co-administration of T cell engagers (signal 1) with either co-stimulatory (signal 2) or cytokine (signal 3) payloads could function in an AND gate configuration (Fig

Muller, W

Front Mol Neurosci 12:143

10.1007/s11357-023-00794-6 12 BejaranoL.BossoG.LouzameJ.SerranoR.GmezCaseroE.MartnezTorrecuadradaJ.et al (2019)

According to Todd Carter, chief scientific officer at Voyager Therapeutics, which is developing a small interfering RNA gene therapy to stop tau production, there was no reason to anticipate that blocking tau protein synthesis would impact the stability of the existing protein