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Some studies suggest betaine may support making skin tone more even

343 Reduced astrocytic homoeostatic support is also evidenced by the loss of endfeet polarisation of AQP4 344 and decreased expression of monocarboxylate transporter 1 345 responsive for lactate supply of neurones

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While their preclinical efficacy is promising, clinical translation has been limited by poor bioavailability

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Their bodies are simply not absorbing the intact molecule