Three of the top five drugs driving the net change in costs per member per month (PMPM) were GLP-1 agonists
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Semaglutide has been shown to reduce -amyloid deposition, improved spatial memory, and enhanced cerebral glucose metabolism (Zhang et al., 2024)
It further reveals how current advances in triple agonists and oral formulations promise to further lower barriers to treatment and enhance therapeutic outcomes
2024 Meta-Analysis Indicates That GLP-1RAs Reduce Adverse CV Events GLP1-RA therapy significantly reduces the risk of major adverse cardiovascular events (MACEs), all-cause mortality, CV mortality, stroke, risk for coronary revascularization, and composite adverse kidney outcomes in both sexes, regardless of a patient's history of cardiovascular disease, BMI or eGFR (Rivera et al, 2024)
Retatrutide has quickly become one of the most talked-about peptides in the United States